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doi: 10.1016/j.freeradbiomed.2011.12.003 140 Perez-BurilloS.Navajas-PorrasB.Lopez-MaldonadoA.Hinojosa-NogueiraD.PastorizaS.Rufian-HenaresJ

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Apart from neutralizing free radicals, N-acetylcysteine also regulates the Foxo3a/TRIM69/p53 pathway attenuating Foxo3a phosphorylation and TRIM69 expression with a subsequent reduction in p53-induced apoptosis [62]