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KLF2 inhibits ferroptosis and improves mitochondrial dysfunction in chondrocyte through SIRT1/GPX4 signaling to improve osteoarthritis

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In summary, our study primarily investigated the beneficial effects of GHK-Cu in UC, using a DSS-induced colitis mouse model and an in vitro co-culture system, suggesting that GHK-Cu may exert anti-inflammatory properties and its role in facilitating the repair of UC by regulating SIRT1/STAT3 signaling pathway