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[2] [11] As of 2026, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and it remains an experimental compound available only within authorised clinical trial settings

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At the 12mg maintenance dose, retatrutide produced significant reductions in systolic blood pressure of approximately 5–7 mmHg from baseline by week 24