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30 3) Interference with melanosome synthesis and transport: Interference with the expression of PMEL can affect melanosome synthesis, while obstruction to melanosome transport can be caused by inhibiting PAR-2

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Standalone or combinatorial regimens designed around potent bio-absorptive reductants, elevating the efficiency of palliative treatment by decreasing or delaying disease progression, will be a welcome step for further trials and those affected by the disease